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    ZFN1 zinc finger protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821230, updated on 6-Oct-2023

    Summary

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    Gene symbol
    ZFN1
    Gene description
    zinc finger protein 1
    Primary source
    Araport:AT3G02830
    Locus tag
    AT3G02830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13E7.23; F13E7_23; PENTA 1; PNT1; zinc finger protein 1
    Summary
    Encodes a zinc finger protein that binds to PORA mRNA in vivo and recruits the Pfr form of phytochrome to the 5'-UTR of PORA mRNA to regulate translation of the mRNA.
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    Genomic context

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    See ZFN1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (613772..616145)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene zinc knuckle (CCHC-type) family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Targeted mutagenesis using zinc-finger nucleases in Arabidopsis. Lloyd A, et al. Proc Natl Acad Sci U S A, 2005 Feb 8. PMID 15677315, Free PMC Article
    2. Phytochrome regulates translation of mRNA in the cytosol. Paik I, et al. Proc Natl Acad Sci U S A, 2012 Jan 24. PMID 22232680, Free PMC Article
    3. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
    4. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Efroni I, et al. Dev Cell, 2013 Feb 25. PMID 23449474, Free PMC Article
    5. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337436.1
    NM_111151.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables mRNA 5'-UTR binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nuclease activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables phytochrome binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 1
    NP_566183.1
    • zinc finger protein 1 (ZFN1); CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571); BEST Arabidopsis thaliana protein match is: zinc finger nuclease 3 (TAIR:AT5G16540.1); Has 1325 Blast hits to 706 proteins in 142 species: Archae - 0; Bacteria - 0; Metazoa - 216; Fungi - 147; Plants - 868; Viruses - 0; Other Eukaryotes - 94 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      613772..616145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111151.5 → NP_566183.1  zinc finger protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566183.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1EBW8, Q8GXX7, Q9M8S4, Q9XFB8
      UniProtKB/TrEMBL
      A0A178VJ68, A0A5S9X8L2
      Conserved Domains (1) summary
      pfam00642
      Location:87 → 112
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    2. NM_001337436.1 → NP_001325699.1  zinc finger protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LM16
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GXX7.1

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