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    cblc Cbl proto-oncogene C, E3 ubiquitin protein ligase [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 101158476, updated on 8-Mar-2024

    Summary

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    Gene symbol
    cblc
    Gene description
    Cbl proto-oncogene C, E3 ubiquitin protein ligase
    See related
    EnsemblRapid:ENSORLG00000013615
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Orthologs
    zebrafish all
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    Genomic context

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    See cblc in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 16 NC_019874.2 (21793635..21808386, complement)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 16 NC_019874.1 (18663366..18678523, complement)

    Chromosome 16 - NC_019874.2Genomic Context describing neighboring genes Neighboring gene trypsin-2 Neighboring gene trypsinogen Neighboring gene BCL3 transcription coactivator Neighboring gene translocase of outer mitochondrial membrane 40 homolog (yeast)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SH3 domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphotyrosine residue binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables receptor tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane raft IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase CBL

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019874.2 Reference ASM223467v1 Primary Assembly

      Range
      21793635..21808386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_020710280.2 → XP_020565939.2  E3 ubiquitin-protein ligase CBL isoform X4

      UniProtKB/TrEMBL
      A0A3P9LMC3
      Related
      ENSORLP00000044381.2, ENSORLT00000039123.2
      Conserved Domains (4) summary
      cd09920
      Location:234 → 328
      SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
      pfam02262
      Location:26 → 153
      Cbl_N; CBL proto-oncogene N-terminal domain 1
      pfam02761
      Location:157 → 240
      Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
      cl17238
      Location:340 → 406
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. XM_023964004.1 → XP_023819772.1  E3 ubiquitin-protein ligase CBL isoform X1

      UniProtKB/TrEMBL
      A0A3P9LMC3
      Related
      ENSORLP00000017078.3, ENSORLT00000017079.3
      Conserved Domains (4) summary
      cd09920
      Location:234 → 328
      SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
      pfam02262
      Location:26 → 153
      Cbl_N; CBL proto-oncogene N-terminal domain 1
      pfam02761
      Location:157 → 240
      Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
      cl17238
      Location:340 → 406
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    3. XM_023964005.1 → XP_023819773.1  E3 ubiquitin-protein ligase CBL isoform X2

      UniProtKB/TrEMBL
      A0A3P9LMC3, H2MER5
      Conserved Domains (4) summary
      cd09920
      Location:234 → 328
      SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
      pfam02262
      Location:26 → 153
      Cbl_N; CBL proto-oncogene N-terminal domain 1
      pfam02761
      Location:157 → 240
      Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
      cl17238
      Location:340 → 405
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    4. XM_023964006.1 → XP_023819774.1  E3 ubiquitin-protein ligase CBL isoform X3

      UniProtKB/TrEMBL
      A0A3P9LMC3
      Related
      ENSORLP00000056950.1, ENSORLT00000066895.1
      Conserved Domains (4) summary
      cd09920
      Location:234 → 328
      SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
      pfam02262
      Location:26 → 153
      Cbl_N; CBL proto-oncogene N-terminal domain 1
      pfam02761
      Location:157 → 240
      Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
      cl17238
      Location:340 → 406
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein
    Heading Accession and Version

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