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    ATP6AP2 ATPase H+ transporting accessory protein 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 100682978, updated on 8-Mar-2024

    Summary

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    Official Symbol
    ATP6AP2provided by VGNC
    Official Full Name
    ATPase H+ transporting accessory protein 2provided by VGNC
    Primary source
    VGNC:VGNC:38267
    See related
    Ensembl:ENSCAFG00845026626
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ATP6AP2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (35099002..35122024)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (22398893..22421901)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (35193579..35216589)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (35178090..35201096)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (35150804..35173213)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119868192 Neighboring gene SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) pseudogene Neighboring gene uncharacterized LOC111094748 Neighboring gene fatty acid-binding protein 5 Neighboring gene mitochondrial pyruvate carrier 1 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. (Pro)renin receptor is required for prorenin-dependent and -independent regulation of vacuolar H⁺-ATPase activity in MDCK.C11 collecting duct cells. Lu X, et al. Am J Physiol Renal Physiol, 2013 Aug 1. PMID 23698123

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. in MDCK cells, the prorenin receptor (atp6ap2) is required for prorenin-dependent and -independent regulation of V-ATPase activity
      Title: (Pro)renin receptor is required for prorenin-dependent and -independent regulation of vacuolar H⁺-ATPase activity in MDCK.C11 collecting duct cells.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    renin receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      35099002..35122024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038449781.1 → XP_038305709.1  renin receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0LU92, A0A8C0S3M3, A0A8C0S419, A0A8I3PTV1, A0A8I3Q0X6
      Related
      ENSCAFP00845036969.1, ENSCAFT00845047106.1
      Conserved Domains (1) summary
      pfam07850
      Location:255 → 351
      Renin_r; Renin receptor-like protein

    2. XM_038449782.1 → XP_038305710.1  renin receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0RIN1
      Conserved Domains (1) summary
      pfam07850
      Location:254 → 350
      Renin_r; Renin receptor-like protein

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      35178090..35201096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038523225.1 → XP_038379153.1  renin receptor isoform X1

      Conserved Domains (1) summary
      pfam07850
      Location:255 → 351
      Renin_r; Renin receptor-like protein

    2. XM_038523226.1 → XP_038379154.1  renin receptor isoform X2

      Conserved Domains (1) summary
      pfam07850
      Location:254 → 350
      Renin_r; Renin receptor-like protein

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      35150804..35173213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038651706.1 → XP_038507634.1  renin receptor isoform X1

      Conserved Domains (1) summary
      pfam07850
      Location:255 → 351
      Renin_r; Renin receptor-like protein

    2. XM_038651707.1 → XP_038507635.1  renin receptor isoform X2

      Conserved Domains (1) summary
      pfam07850
      Location:254 → 350
      Renin_r; Renin receptor-like protein

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      35193579..35216589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038587190.1 → XP_038443118.1  renin receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0LU92, A0A8C0S3M3, A0A8C0S419, A0A8I3PTV1, A0A8I3Q0X6
      Conserved Domains (1) summary
      pfam07850
      Location:255 → 351
      Renin_r; Renin receptor-like protein

    2. XM_038587191.1 → XP_038443119.1  renin receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0RIN1
      Conserved Domains (1) summary
      pfam07850
      Location:254 → 350
      Renin_r; Renin receptor-like protein

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      22398893..22421901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038464383.1 → XP_038320311.1  renin receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0LU92, A0A8C0S3M3, A0A8C0S419, A0A8I3PTV1, A0A8I3Q0X6
      Conserved Domains (1) summary
      pfam07850
      Location:255 → 351
      Renin_r; Renin receptor-like protein

    2. XM_038464384.1 → XP_038320312.1  renin receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0RIN1
      Conserved Domains (1) summary
      pfam07850
      Location:254 → 350
      Renin_r; Renin receptor-like protein
    Nucleotide Protein
    Heading Accession and Version

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