PubMed for id: 270787

Year	Number of Results
2000	2
2001	1
2002	1
2003	2
2004	3
2005	4
2006	9
2007	5
2024	0

1

Structural insights into the recognition of substrates and activators by the OSR1 kinase.

Villa F, Goebel J, Rafiqi FH, Deak M, Thastrup J, Alessi DR, van Aalten DM. Villa F, et al. EMBO Rep. 2007 Sep;8(9):839-45. doi: 10.1038/sj.embor.7401048. Epub 2007 Aug 17. EMBO Rep. 2007. PMID: 17721439 Free PMC article.

2

A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.

Gagnon KB, England R, Delpire E. Gagnon KB, et al. Cell Physiol Biochem. 2007;20(1-4):131-42. doi: 10.1159/000104161. Cell Physiol Biochem. 2007. PMID: 17595523 Free article.

3

Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation.

Gagnon KB, England R, Diehl L, Delpire E. Gagnon KB, et al. Am J Physiol Cell Physiol. 2007 May;292(5):C1809-15. doi: 10.1152/ajpcell.00580.2006. Epub 2007 Jan 31. Am J Physiol Cell Physiol. 2007. PMID: 17267545 Free article.

4

Cotransporters, WNKs and hypertension: important leads from the study of monogenetic disorders of blood pressure regulation.

Flatman PW. Flatman PW. Clin Sci (Lond). 2007 Feb;112(4):203-16. doi: 10.1042/CS20060225. Clin Sci (Lond). 2007. PMID: 17223794 Review.

5

Genome-wide analysis of SPAK/OSR1 binding motifs.

Delpire E, Gagnon KB. Delpire E, et al. Physiol Genomics. 2007 Jan 17;28(2):223-31. doi: 10.1152/physiolgenomics.00173.2006. Epub 2006 Oct 10. Physiol Genomics. 2007. PMID: 17032814

6

TRAIL-induced cleavage and inactivation of SPAK sensitizes cells to apoptosis.

Polek TC, Talpaz M, Spivak-Kroizman TR. Polek TC, et al. Biochem Biophys Res Commun. 2006 Oct 27;349(3):1016-24. doi: 10.1016/j.bbrc.2006.08.118. Epub 2006 Aug 28. Biochem Biophys Res Commun. 2006. PMID: 16950202

7

Molecular mechanisms and regulation of furosemide-sensitive Na-K-Cl cotransporters.

Giménez I. Giménez I. Curr Opin Nephrol Hypertens. 2006 Sep;15(5):517-23. doi: 10.1097/01.mnh.0000242178.44576.b0. Curr Opin Nephrol Hypertens. 2006. PMID: 16914965 Review.

8

WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells.

Anselmo AN, Earnest S, Chen W, Juang YC, Kim SC, Zhao Y, Cobb MH. Anselmo AN, et al. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10883-8. doi: 10.1073/pnas.0604607103. Epub 2006 Jul 10. Proc Natl Acad Sci U S A. 2006. PMID: 16832045 Free PMC article.

9

SPAK and OSR1, key kinases involved in the regulation of chloride transport.

Delpire E, Gagnon KB. Delpire E, et al. Acta Physiol (Oxf). 2006 May-Jun;187(1-2):103-13. doi: 10.1111/j.1748-1716.2006.01565.x. Acta Physiol (Oxf). 2006. PMID: 16734747 Review.

10

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.

Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR. Vitari AC, et al. Biochem J. 2006 Jul 1;397(1):223-31. doi: 10.1042/BJ20060220. Biochem J. 2006. PMID: 16669787 Free PMC article.

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