Lipopolysaccharide effect on scavenger receptor MARCO deficient-dendritic cells
Summary:
Analysis of spleen dendritic cells (DCs) isolated from macrophage receptor with collagenous structure (MARCO)-knockout animals and cultured in media containing TLR agonist LPS. MARCO is part of the innate antimicrobial immune system. Results provide insight into the role of MARCO in activated DCs.
Kissick HT, Dunn LK, Ghosh S, Nechama M et al. The scavenger receptor MARCO modulates TLR-induced responses in dendritic cells. PLoS One 2014;9(8):e104148. PMID: 25089703