DataSet Record GDS5451: Expression Profiles Data Analysis Tools Sample Subsets
Title: Pregnancy effect on liver of cytochrome P450 2D6 hepatic metabolism model: time course
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Summary: Analysis of livers of Cytochrome P450 2D6 (CYP2D6)-humanized mice at various gestational stages: pre-pregnancy, 21 days of pregnancy, and 7 days postpartum. Results provide insight into molecular mechanisms underlying increased CYP2D6-mediated drug metabolism during pregnancy.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Koh KH, Pan X, Zhang W, McLachlan A et al. Krüppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice. Mol Pharmacol 2014 Dec;86(6):727-35. PMID: 25217496
Reference Series: GSE50166 Sample count: 6
Value type: transformed count Series published: 2014/12/04