Analysis of peripheral blood from patients with bipolar disorder before and 1 month after lithium treatment. Response of patients to lithium assessed after 6 months. Results identify a gene expression signature for the response to lithium treatment in patients with bipolar disorder.
Beech RD, Leffert JJ, Lin A, Sylvia LG et al. Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS). Pharmacogenomics J 2014 Apr;14(2):182-91. PMID: 23670706
