Ankle joint response to the induction of arthritis
Summary:
Analysis of ankle joints of wild type animals following treatment with sera from K/BxN mice to induce arthritis. Results compared to arthritic ankles from Mmp-8 deficient mutants (GDS5243) and provide insight into the role of Mmp-8 in the pathogenesis of arthritis.
García S, Forteza J, López-Otin C, Gómez-Reino JJ et al. Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model. Arthritis Res Ther 2010;12(6):R224. PMID: 21190566
