Ubiquitin carboxyl hydrolase BAP1 depletion effect on osteosarcoma cell line
Summary:
Analysis of U2OS osteosarcoma cells depleted for the ubiquitin carboxyl hydrolase BAP1. BAP1 is a deubiquitinating enzyme. Results provide insight into the role of BAP1 in transcriptional regulation.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Yu H, Mashtalir N, Daou S, Hammond-Martel I et al. The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression. Mol Cell Biol 2010 Nov;30(21):5071-85. PMID: 20805357
