DataSet Record GDS5063: Expression Profiles Data Analysis Tools Sample Subsets
Title: Conventional cigarette or modified-risk tobacco product smoke effect on lung bronchial epithelium: dose response
Cluster AnalysisGDS5063 Cluster Image
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Summary: Analysis of left lung bronchi from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.
Organism: Rattus norvegicus
Platform: GPL1355: [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
  • Kogel U, Schlage WK, Martin F, Xiang Y et al. A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes. Food Chem Toxicol 2014 Jun;68:204-17. PMID: 24632068
Reference Series: GSE50254 Sample count: 25
Value type: transformed count Series published: 2014/05/15