db/db model of obesity-induced type 2 diabetes: neuroretina
Summary:
Analysis of neuroretina from 8-week C57BLKsJ-db/db diabetic mice. These leptin-receptor-deficient db/db mice have been shown to exhibit early features of diabetic retinopathy (DR). Results provide insight into the molecular mechanisms underlying early diabetic retinal neurodegeneration.
Bogdanov P, Corraliza L, Villena JA, Carvalho AR et al. The db/db mouse: a useful model for the study of diabetic retinal neurodegeneration. PLoS One 2014;9(5):e97302. PMID: 24837086
