Treatment-naive, chronic hepatitis C virus-infected patients: CD4+ and CD8+ T-lymphocytes
Summary:
Analysis of antigen-specific CD4+ and CD8+ T-cells from treatment-naive, chronic hepatitis C virus (CHC) patients with high or low viral loads. Results provide insight into molecular mechanisms underlying functional impairment differences between CD4+ and CD8+ T-cells during CHC infection.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Zhao BB, Zheng SJ, Gong LL, Wang Y et al. T lymphocytes from chronic HCV-infected patients are primed for activation-induced apoptosis and express unique pro-apoptotic gene signature. PLoS One 2013;8(10):e77008. PMID: 24130824
