Cigarette smoke and second-hand smoke effects on obese male hearts
Summary:
Analysis of heart from high-fat diet-induced obese (DIO) C57BL/6 males exposed to mainstream (MS) or sidestream (SS) cigarette smoke. Smoking and obesity are risk factors for heart disease. Results provide insight into molecular mechanisms underlying cardiac responses of smoke-exposed DIO animals.
Tilton SC, Karin NJ, Webb-Robertson BJ, Waters KM et al. Impaired transcriptional response of the murine heart to cigarette smoke in the setting of high fat diet and obesity. Chem Res Toxicol 2013 Jul 15;26(7):1034-42. PMID: 23786483