FHH.Pkhd1 model of autosomal recessive polycystic kidney disease
Summary:
Analysis of kidneys from 30 day-old males representing SD, FHH, PCK, and FHH.Pkhd1 strains. The FHH.Pkhd1 strain carries the PCK Pkhd1 mutation but is resistant to the development of ARPKD. Results provide insight into the molecular mechanisms that modulate ARPKD disease progression and severity.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
O'Meara CC, Hoffman M, Sweeney WE Jr, Tsaih SW et al. Role of genetic modifiers in an orthologous rat model of ARPKD. Physiol Genomics 2012 Aug 1;44(15):741-53. PMID: 22669842
