Primary hepatocyte response to interferon-α or interleukin 28B: time course
Summary:
Analysis of primary hepatocytes up to 24 hrs after treatment with cytokines: interferon (IFN)-α or interleukin 28B (IL28B, a type III IFN). Members of type III IFN system possess antiviral activities against Hepatitis C Virus (HCV). Results provide insight into role of III IFNs in HCV infection.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Thomas E, Gonzalez VD, Li Q, Modi AA et al. HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons. Gastroenterology 2012 Apr;142(4):978-88. PMID: 22248663
