Analysis of explanted livers of 4 patients with HBV-associated ALF who underwent liver transplantation. Liver has inherent regenerative capacity via hepatic stem/progenitor cells (HSPC) when hepatic loss is massive. Results provide insight into role of HSPC in liver regeneration associated with ALF.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Nissim O, Melis M, Diaz G, Kleiner DE et al. Liver regeneration signature in hepatitis B virus (HBV)-associated acute liver failure identified by gene expression profiling. PLoS One 2012;7(11):e49611. PMID: 23185381