Dopamine β-hydroxylase knockout effect on embryonic heart
Summary:
Analysis of adrenergic-deficient (Dbh-/-) E10.5 hearts. Adrenergic hormones are essential for early heart development. Results provide insight into molecular mechanisms that mediate adrenergic actions in early heart development.
Osuala K, Baker CN, Nguyen HL, Martinez C et al. Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism. Physiol Genomics 2012 Oct 2;44(19):934-47. PMID: 22911456
