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DataSet Record GDS4247:
Expression Profiles
Data Analysis Tools
Sample Subsets
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Title:
| Cystic fibrosis: trachea, bronchus and distal lung | |
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Summary:
| Analysis of trachea, bronchus and distal lung from newborn pigs with cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations. Cystic fibrosis (CF) pigs develop lung disease. Results provide insight into CF lung disease pathogenesis. |
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| Organism:
| Sus scrofa |
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Platform:
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GPL3533:
[Porcine] Affymetrix Porcine Genome Array |
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| Citations: | - Stoltz DA, Meyerholz DK, Pezzulo AA, Ramachandran S et al. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Sci Transl Med 2010 Apr 28;2(29):29ra31. PMID: 20427821
- Pezzulo AA, Tang XX, Hoegger MJ, Abou Alaiwa MH et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature 2012 Jul 4;487(7405):109-13. PMID: 22763554
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Reference Series:
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GSE21071 |
Sample count:
| 40 |
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Value type:
| count |
Series published:
| 2010/09/17 |
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