Cyclophosphamide effect on bone marrow: time course
Summary:
Analysis of bone marrow (a primary lymphoid organ) from tumor-bearing animals for up to 5 days after a single chemotherapeutic treatment of cyclophosphamide (CTX). Results provide insight into the CTX-mediated effects responsible for the antitumor efficacy of chemoimmunotherapy.
Moschella F, Valentini M, Aricò E, Macchia I et al. Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide. Cancer Res 2011 May 15;71(10):3528-39. PMID: 21444678