Dextran sodium sulfate-induced colitis model: time course
Summary:
Analysis of colon from C57BL/6J 12-14wk-olds treated with DSS for up to 6 days. DSS model emulates clinical and histopathological features of ulcerative colitis (UC), a type of Inflammatory Bowel Disease (IBD). Results provide insight into molecular mechanisms underlying development of DSS colitis.
Fang K, Bruce M, Pattillo CB, Zhang S et al. Temporal genomewide expression profiling of DSS colitis reveals novel inflammatory and angiogenesis genes similar to ulcerative colitis. Physiol Genomics 2011 Jan 7;43(1):43-56. PMID: 20923862
