Early-passage induced pluripotent stem (iPS) cells derived from various somatic cell populations
Summary:
Analysis of iPSCs (at p4) derived from different cell types (fibroblasts, hematopoietic, myogenic cells) through ectopic expression of transcription factors Oct4, Sox2, Klf4, cMyc. Results provide insight into the influence of cellular origin on transcriptional patterns of derivative iPSCs.
Polo JM, Liu S, Figueroa ME, Kulalert W et al. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol 2010 Aug;28(8):848-55. PMID: 20644536
