DataSet Record GDS3630: Expression Profiles Data Analysis Tools Sample Subsets
Title: Monozygotic and dizygotic twin pairs: intestinal mucosa
Cluster AnalysisGDS3630 Cluster Image
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Summary: Analysis of healthy intestinal mucosa biopsies from 10 monozygotic and 10 dizygotic twin pairs. Barrier organs such as the gut are exposed to continual environmental challenge. Results provide insight into genetic and non-genetic determinants of gene expression.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Häsler R, Begun A, Freitag-Wolf S, Kerick M et al. Genetic control of global gene expression levels in the intestinal mucosa: a human twin study. Physiol Genomics 2009 Jun 10;38(1):73-9. PMID: 19276242
  • Lepage P, Häsler R, Spehlmann ME, Rehman A et al. Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology 2011 Jul;141(1):227-36. PMID: 21621540
Reference Series: GSE7821 Sample count: 40
Value type: transformed count Series published: 2009/05/05