Analysis of cells overexpressing NOR1 or the EWS/NOR1 fusion gene. NOR1 encodes an orphan nuclear receptor. The EWS gene is involved in various malignancies by way of chromosomal translocations, and the EWS/NOR1 gene fusion is implicated in the pathogenesis of extraskeletal myxoid chondrosarcomas.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Ohkura N, Nagamura Y, Tsukada T. Differential transactivation by orphan nuclear receptor NOR1 and its fusion gene product EWS/NOR1: possible involvement of poly(ADP-ribose) polymerase I, PARP-1. J Cell Biochem 2008 Oct 15;105(3):785-800. PMID: 18680143
