DataSet Record GDS3344: Expression Profiles Data Analysis Tools Sample Subsets
Title: FHL2 deficiency effect on spontaneously immortalized embryonic fibroblasts
Cluster AnalysisGDS3344 Cluster Image
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Summary: Analysis of spontaneously immortalized embryonic fibroblasts (EFs) lacking the LIM-only protein FHL2. FHL2 deficiency results in reduced proliferative capacity of spontaneously immortalized EFs. Results provide insight into the role of FLH2 in cell cycle and cell proliferation.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citations:
  • Labalette C, Nouët Y, Sobczak-Thepot J, Armengol C et al. The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. J Biol Chem 2008 May 30;283(22):15201-8. PMID: 18378678
  • Labalette C, Nouët Y, Levillayer F, Armengol C et al. The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways. PLoS One 2008;3(11):e3761. PMID: 19018287
Reference Series: GSE10902 Sample count: 6
Value type: transformed count Series published: 2008/06/06