DataSet Record GDS2686: Expression Profiles Data Analysis Tools Sample Subsets
Title: MyD88 deficient macrophage response to zymosan
Cluster AnalysisGDS2686 Cluster Image
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Summary: Analysis of MyD88-deficient macrophages treated with fungal cell wall component zymosan. Zymosan-induced Toll-like receptor (TLR) signaling is transduced via adaptor protein MyD88. Results provide insight into the role of non-TLR innate immune signaling in response to zymosan and pathogenic fungi.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Goodridge HS, Simmons RM, Underhill DM. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol 2007 Mar 1;178(5):3107-15. PMID: 17312158
Reference Series: GSE6376 Sample count: 4
Value type: transformed count Series published: 2007/01/30