DataSet Record GDS2602: Expression Profiles Data Analysis Tools Sample Subsets
Title: COX-1 or COX-2 knockout effect in brain
Cluster AnalysisGDS2602 Cluster Image
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Summary: Analysis of cortex and hippocampus in cyclooxygenase (COX)-1 and COX-2 knockouts. COX-1 and COX-2 produce prostanoids from arachidonic acid. Results indicate COX-1 and COX-2 differentially modulate brain gene expression, and give insight into therapeutic and toxicologic effects of COX inhibition.
Organism: Mus musculus
Platform: GPL4006: NIH/NIA_mouse_17k
Citation:
  • Toscano CD, Prabhu VV, Langenbach R, Becker KG et al. Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain. Genome Biol 2007;8(1):R14. PMID: 17266762
Reference Series: GSE5342 Sample count: 30
Value type: Z-score Series published: 2007/02/05