Analysis of T cells anergized in vitro with plate-bound anti-CD3. Anergy is a hyporesponsive state resulting from the engagement of the T cell receptor in the absence of CD28 costimulation. Results provide insight into the mechanistic basis of T cell anergy.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Zha Y, Marks R, Ho AW, Peterson AC et al. T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha. Nat Immunol 2006 Nov;7(11):1166-73. PMID: 17028589
