DataSet Record GDS1995: Expression Profiles Data Analysis Tools Sample Subsets
Title: Age effect on healing femoral fractures: time course
Cluster AnalysisGDS1995 Cluster Image
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Summary: Analysis of healing femurs of 6, 26, and 52-week-old Sprague-Dawley females at various time points up to 6 weeks after fracture. 6, 26, and 52-week-old animals regain normal skeletal biomechanics 4 weeks, 10 weeks, and 6 months after fracture, respectively.
Organism: Rattus norvegicus
Platform: GPL85: [RG_U34A] Affymetrix Rat Genome U34 Array
Citations:
  • Meyer MH, Etienne W, Meyer RA Jr. Altered mRNA expression of genes related to nerve cell activity in the fracture callus of older rats: A randomized, controlled, microarray study. BMC Musculoskelet Disord 2004 Aug 3;5:24. PMID: 15291962
  • Meyer RA Jr, Desai BR, Heiner DE, Fiechtl J et al. Young, adult, and old rats have similar changes in mRNA expression of many skeletal genes after fracture despite delayed healing with age. J Orthop Res 2006 Oct;24(10):1933-44. PMID: 16894589
  • Meyer MH, Meyer RA Jr. Genes with greater up-regulation in the fracture callus of older rats with delayed healing. J Orthop Res 2007 Apr;25(4):488-94. PMID: 17205564
  • Meyer MH, Meyer RA Jr. Altered expression of mitochondrial genes in response to fracture in old rats. Acta Orthop 2006 Dec;77(6):944-51. PMID: 17260206
Reference Series: GSE1371 Sample count: 18
Value type: count Series published: 2004/10/06