Bleomycin effect on mutagen-sensitive lymphoblastoid cell lines
Summary:
Analysis of mutagen-sensitive lymphoblastoid cell lines after exposure to bleomycin. Mutagen-sensitive cells exhibit a high number of bleomycin-induced chromatid breaks. Mutagen sensitivity (MS) reflects an individual's susceptibility to sporadic cancers. Results identify genes involved in MS.
Cloos J, de Boer WP, Snel MH, van den Ijssel P et al. Microarray analysis of bleomycin-exposed lymphoblastoid cells for identifying cancer susceptibility genes. Mol Cancer Res 2006 Feb;4(2):71-7. PMID: 16513838
