Breast cancer cell lines response to chemotherapeutic drugs: time course
Summary:
Analysis of 4 breast cell lines treated for up to 36 hrs with the chemotherapeutic agents 5-fluorouracil (5FU), doxorubicin (DOX), or etoposide (ETOP), a drug mechanistically similar to DOX. Expression profiles for DOX- and 5FU-treated cells were used to successfully predict the response to ETOP.
GPL550:
UNC compugen oligo array for toxgenomics study
Citation:
Troester MA, Hoadley KA, Parker JS, Perou CM. Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell lines. Environ Health Perspect 2004 Nov;112(16):1607-13. PMID: 15598611
