Analysis of umbilical cord blood-derived mast cells 2 hours post stimulation by high-affinity IgE receptor (FcεRI). Cells incubated with myeloma IgE and IL-4 prior to stimulation. Cells activated via FcεRI with anti-IgE antibody to induce release of antihistamines and other inflammation mediators.
Sayama K, Diehn M, Matsuda K, Lunderius C et al. Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11. BMC Immunol 2002 Jun 12;3:5. PMID: 12079505
