Analysis of cultured 3T3-F442A adipocytes treated with 500 nM growth hormone (GH). Adipocytes examined at various time points up to 48 hours following treatment with GH. Chronic GH treatment induces metabolic changes consistent with insulin resistance in 3T3-F442A adipocytes.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Huo JS, McEachin RC, Cui TX, Duggal NK et al. Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH. J Biol Chem 2006 Feb 17;281(7):4132-41. PMID: 16326703