Serum response factor null mutation effect on neonatal cardiomyocytes
Summary:
Analysis of serum response factor (SRF)-null neonatal cardiomyocytes. SRF is a transcriptional regulator required for mesodermal development and implicated in myogenesis. Results provide insight into the role of SRF in regulating genetic programs important for controlling cardiomyocyte function.
Balza RO Jr, Misra RP. Role of the serum response factor in regulating contractile apparatus gene expression and sarcomeric integrity in cardiomyocytes. J Biol Chem 2006 Mar 10;281(10):6498-510. PMID: 16368687
