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Flurbiprofen Therapy and CYP2C9 Genotype.
2019 Feb 11. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–.
2019 Feb 11. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–.
PMID: 30742399
Free Books & Documents.
Review.
Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?
Agúndez JA, García-Martín E, Martínez C.
Agúndez JA, et al.
Expert Opin Drug Metab Toxicol. 2009 Jun;5(6):607-20. doi: 10.1517/17425250902970998.
Expert Opin Drug Metab Toxicol. 2009.
PMID: 19422321
Review.
Item in Clipboard
Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes.
Lee CR, Pieper JA, Frye RF, Hinderliter AL, Blaisdell JA, Goldstein JA.
Lee CR, et al.
Eur J Clin Pharmacol. 2003 Apr;58(12):791-4. doi: 10.1007/s00228-003-0574-6. Epub 2003 Feb 26.
Eur J Clin Pharmacol. 2003.
PMID: 12698304
Clinical Trial.
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Effects of CYP2C9*1/*3 genotype on the pharmacokinetics of flurbiprofen in Korean subjects.
Lee YJ, Byeon JY, Kim YH, Kim SH, Choi CI, Bae JW, Sohn UD, Jang CG, Lee J, Lee SY.
Lee YJ, et al.
Arch Pharm Res. 2015 Jun;38(6):1232-7. doi: 10.1007/s12272-015-0580-0. Epub 2015 Feb 25.
Arch Pharm Res. 2015.
PMID: 25712887
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CYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drug.
Vogl S, Lutz RW, Schönfelder G, Lutz WK.
Vogl S, et al.
PLoS One. 2015 Mar 16;10(3):e0120403. doi: 10.1371/journal.pone.0120403. eCollection 2015.
PLoS One. 2015.
PMID: 25775139
Free PMC article.
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