Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach

Protein Cell. 2015 Dec;6(12):924-8. doi: 10.1007/s13238-015-0225-6.

Yuwei Bai^{1

2}, Shinya Tashiro³, Satoru Nagatoishi³, Toru Suzuki⁴, Dongke Yan^{1

2}, Ruihua Liu^{1

2}, Kouhei Tsumoto⁵, Mark Bartlam^{6

7}, Tadashi Yamamoto⁴

¹ State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, China.
² College of Life Sciences, Nankai University, Tianjin, 300071, China.
³ Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.
⁴ Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Onna-son, Kunigami, Okinawa, 904-0412, Japan.
⁵ Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. tsumoto@ims.u-tokyo.ac.jp.
⁶ State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, China. bartlam@nankai.edu.cn.
⁷ College of Life Sciences, Nankai University, Tianjin, 300071, China. bartlam@nankai.edu.cn.

No abstract available

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