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PubMed for id: 4503529

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eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation.
Schmidt T, Dabrowska A, Waldron JA, Hodge K, Koulouras G, Gabrielsen M, Munro J, Tack DC, Harris G, McGhee E, Scott D, Carlin LM, Huang D, Le Quesne J, Zanivan S, Wilczynska A, Bushell M. Schmidt T, et al. Nucleic Acids Res. 2023 Feb 28;51(4):1859-1879. doi: 10.1093/nar/gkad030. Nucleic Acids Res. 2023. PMID: 36727461 Free PMC article.
eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast Cancer Cell Model.
González-Ortiz A, Pulido-Capiz A, Castañeda-Sánchez CY, Ibarra-López E, Galindo-Hernández O, Calderón-Fernández MA, López-Cossio LY, Díaz-Molina R, Chimal-Vega B, Serafín-Higuera N, Córdova-Guerrero I, García-González V. González-Ortiz A, et al. Cells. 2022 Dec 15;11(24):4069. doi: 10.3390/cells11244069. Cells. 2022. PMID: 36552834 Free PMC article.
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P. George J, et al. Cell Rep. 2021 Nov 2;37(5):109934. doi: 10.1016/j.celrep.2021.109934. Cell Rep. 2021. PMID: 34731628 Free PMC article.