Isolation of a cDNA encoding a mouse TFIID subunit containing histone H4 homology

Gene. 1995 Aug 19;161(2):301-2. doi: 10.1016/0378-1119(95)00285-e.

Abstract

A cDNA encoding a mouse transcription factor IID (TFIID) subunit, containing histone H4 homology, was cloned and sequenced. The predicted 678-amino-acid (aa) sequence of this molecule showed 97 and 41% identity to the human and Drosophila melanogaster homologues, respectively. Four putative direct repeats were found in the most highly conserved region in the central part of this protein.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Cloning, Molecular
  • Conserved Sequence
  • DNA, Complementary / genetics*
  • DNA, Complementary / isolation & purification
  • Drosophila melanogaster
  • Histones / genetics*
  • Humans
  • Mice
  • Molecular Sequence Data
  • Protein Conformation
  • Repetitive Sequences, Nucleic Acid
  • Sequence Homology, Amino Acid
  • Species Specificity
  • Transcription Factor TFIID
  • Transcription Factors / chemistry
  • Transcription Factors / genetics*

Substances

  • DNA, Complementary
  • Histones
  • Transcription Factor TFIID
  • Transcription Factors

Associated data

  • GENBANK/D49439