PubMed (MeSH Keyword) for id: 161930

Year	Number of Results
1981	2
1983	1
2004	3
2005	2
2006	8
2007	14
2008	5
2009	8
2010	9
2011	7
2012	8
2013	10
2014	9
2015	6
2016	6
2018	4
2019	4
2020	4
2021	2
2022	1
2023	1
2024	0

1

Icilin, a cool/cold-inducing agent, alleviates lipopolysaccharide-induced septic sickness responses in mice.

Komura M, Miyata S, Yoshimura R. Komura M, et al. Neurosci Lett. 2023 Nov 1;816:137492. doi: 10.1016/j.neulet.2023.137492. Epub 2023 Sep 22. Neurosci Lett. 2023. PMID: 37742941

2

Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP₂.

Yin Y, Zhang F, Feng S, Butay KJ, Borgnia MJ, Im W, Lee SY. Yin Y, et al. Science. 2022 Oct 14;378(6616):eadd1268. doi: 10.1126/science.add1268. Epub 2022 Oct 14. Science. 2022. PMID: 36227998 Free PMC article.

3

The cold receptor TRPM8 activation leads to attenuation of endothelium-dependent cerebral vascular functions during head cooling.

Fedinec AL, Liu J, Zhang R, Harsono M, Pourcyrous M, Parfenova H. Fedinec AL, et al. J Cereb Blood Flow Metab. 2021 Nov;41(11):2897-2906. doi: 10.1177/0271678X211018035. Epub 2021 May 20. J Cereb Blood Flow Metab. 2021. PMID: 34013806 Free PMC article.

4

Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.

Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H. Kobayashi JI, et al. Bioorg Med Chem. 2021 Jan 15;30:115903. doi: 10.1016/j.bmc.2020.115903. Epub 2020 Dec 3. Bioorg Med Chem. 2021. PMID: 33333445

5

Why wild giant pandas frequently roll in horse manure.

Zhou W, Yang S, Li B, Nie Y, Luo A, Huang G, Liu X, Lai R, Wei F. Zhou W, et al. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32493-32498. doi: 10.1073/pnas.2004640117. Epub 2020 Dec 7. Proc Natl Acad Sci U S A. 2020. PMID: 33288697 Free PMC article.

6

Naked mole-rats lack cold sensitivity before and after nerve injury.

Poulson SJ, Aldarraji A, Arain II, Dziekonski N, Motlana K, Riley R, Holmes MM, Martin LJ. Poulson SJ, et al. Mol Pain. 2020 Jan-Dec;16:1744806920955103. doi: 10.1177/1744806920955103. Mol Pain. 2020. PMID: 32880221 Free PMC article.

7

The super-cooling compound icilin stimulates c-Fos and Egr-1 expression and activity involving TRPM8 channel activation, Ca²⁺ ion influx and activation of the ternary complex factor Elk-1.

Ulrich M, Wissenbach U, Thiel G. Ulrich M, et al. Biochem Pharmacol. 2020 Jul;177:113936. doi: 10.1016/j.bcp.2020.113936. Epub 2020 Mar 26. Biochem Pharmacol. 2020. PMID: 32224140

8

Pharmacological inhibition of TRPM8-induced gene transcription.

Thiel G, Backes TM, Welck J, Steinhausen S, Fischer AL, Langfermann DS, Ulrich M, Wissenbach U, Rössler OG. Thiel G, et al. Biochem Pharmacol. 2019 Dec;170:113678. doi: 10.1016/j.bcp.2019.113678. Epub 2019 Oct 22. Biochem Pharmacol. 2019. PMID: 31654626

9

TRPM8-mediated cutaneous stimulation modulates motor neuron activity during treadmill stepping in mice.

Tamura K, Sugita S, Tokunaga T, Minegishi Y, Ota N. Tamura K, et al. J Physiol Sci. 2019 Nov;69(6):931-938. doi: 10.1007/s12576-019-00707-3. Epub 2019 Sep 3. J Physiol Sci. 2019. PMID: 31482469 Free PMC article.

10

Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice.

Jall S, Finan B, Collden G, Fischer K, Dong X, Tschöp MH, Müller TD, Clemmensen C. Jall S, et al. Mol Metab. 2019 May;23:75-81. doi: 10.1016/j.molmet.2019.02.011. Epub 2019 Mar 7. Mol Metab. 2019. PMID: 30902502 Free PMC article.

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