Abstract
A pandemic (H1N1) 2009 virus strain carrying the D222G mutation was identified in a severely ill man and was transmitted to a household contact. Only mild illness developed in the contact, despite his obesity and diabetes. The isolated virus reacted fully with an antiserum against the pandemic vaccine strain.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Amino Acid Substitution
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Disease Outbreaks*
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Hemagglutinin Glycoproteins, Influenza Virus / genetics*
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Humans
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Influenza A Virus, H1N1 Subtype / genetics*
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Influenza A Virus, H1N1 Subtype / isolation & purification
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Influenza, Human / epidemiology
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Influenza, Human / physiopathology
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Influenza, Human / transmission*
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Influenza, Human / virology*
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Male
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Middle Aged
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Mutation, Missense*
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Phylogeny
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RNA, Viral / analysis
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RNA, Viral / genetics
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Retrospective Studies
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Sequence Analysis, RNA
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Severity of Illness Index
Substances
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Hemagglutinin Glycoproteins, Influenza Virus
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RNA, Viral