Characterization of the genes for mouse LERK-3/Ephrin-A3 (Epl3), mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6): conservation of intron/exon structure

Genomics. 1998 Jan 1;47(1):131-5. doi: 10.1006/geno.1997.5088.

Abstract

We have isolated the genes for the eph receptor family ligands mouse LERK-3/Ephrin-A3 (Epl3), mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6). These genes show a high level of conservation in their intron/exon structures encoding the receptor-binding region. In addition, the nucleotide sequences of the genes reveal the predicted cDNA sequence of mouse LERK-3/Ephrin-A3, mouse LERK-4/Ephrin-A4, and human LERK-6/Ephrin-A2.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • Conserved Sequence
  • Ephrin-A2
  • Ephrin-A3
  • Ephrin-A4
  • Exons
  • Humans
  • In Situ Hybridization / methods
  • Introns
  • Membrane Proteins / genetics*
  • Membrane Proteins / metabolism
  • Mice
  • Molecular Sequence Data
  • Protein Biosynthesis
  • Restriction Mapping
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism

Substances

  • Ephrin-A2
  • Ephrin-A3
  • Ephrin-A4
  • Membrane Proteins
  • Transcription Factors

Associated data

  • GENBANK/U92885
  • GENBANK/U92889
  • GENBANK/U92890
  • GENBANK/U92893
  • GENBANK/U92894
  • GENBANK/U92896