PubMed (GeneRIF) for id: 66612

Year	Number of Results
2013	2
2014	1
2015	3
2016	3
2017	5
2019	5
2020	3
2021	4
2022	1
2023	6
2024	1

1

Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis.

Brown RDR, Green CD, Weigel C, Ni B, Celi FS, Proia RL, Spiegel S. Brown RDR, et al. Mol Metab. 2024 Jan;79:101851. doi: 10.1016/j.molmet.2023.101851. Epub 2023 Dec 9. Mol Metab. 2024. PMID: 38081412 Free PMC article.

2

Histone acetylation regulates ORMDL3 expression-mediated NLRP3 inflammasome overexpression during RSV-allergic exacerbation mice.

Cheng Q, He F, Zhao W, Xu X, Shang Y, Huang W. Cheng Q, et al. J Cell Physiol. 2023 Dec;238(12):2904-2923. doi: 10.1002/jcp.31141. Epub 2023 Oct 25. J Cell Physiol. 2023. PMID: 37877592

3

ORMDL3‑mediated bronchial epithelial pyroptosis leads to lung inflammation in obese mice with asthma.

Liu F, Sun Y, Zhou Y, Gao Y, Song Q, Yang J, Xu C, Li G. Liu F, et al. Mol Med Rep. 2023 Oct;28(4):186. doi: 10.3892/mmr.2023.13073. Epub 2023 Aug 18. Mol Med Rep. 2023. PMID: 37594074 Free PMC article.

4

Ormdl3 regulation of specific ceramides is dispensable for mouse β-cell function and glucose homeostasis under obesogenic conditions.

Hurley LD, Lee H, Wade G, Simcox J, Engin F. Hurley LD, et al. Front Endocrinol (Lausanne). 2023 Apr 14;14:1170461. doi: 10.3389/fendo.2023.1170461. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37124760 Free PMC article.

5

Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice.

James BN, Weigel C, Green CD, Brown RDR, Palladino END, Tharakan A, Milstien S, Proia RL, Martin RK, Spiegel S. James BN, et al. FASEB J. 2023 Mar;37(3):e22799. doi: 10.1096/fj.202201821R. FASEB J. 2023. PMID: 36753412 Free PMC article.

6

The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway.

Shao Y, Xu Y, Di H, Shi X, Wang Y, Liu H, Song L. Shao Y, et al. IET Nanobiotechnol. 2023 May;17(3):182-196. doi: 10.1049/nbt2.12113. Epub 2023 Jan 20. IET Nanobiotechnol. 2023. PMID: 36680386 Free PMC article.

7

Ablation of ORMDL3 impairs adipose tissue thermogenesis and insulin sensitivity by increasing ceramide generation.

Song Y, Zan W, Qin L, Han S, Ye L, Wang M, Jiang B, Fang P, Liu Q, Shao C, Gong Y, Li P. Song Y, et al. Mol Metab. 2022 Feb;56:101423. doi: 10.1016/j.molmet.2021.101423. Epub 2021 Dec 22. Mol Metab. 2022. PMID: 34954108 Free PMC article.

8

Crosstalk between ORMDL3, serine palmitoyltransferase, and 5-lipoxygenase in the sphingolipid and eicosanoid metabolic pathways.

Bugajev V, Paulenda T, Utekal P, Mrkacek M, Halova I, Kuchar L, Kuda O, Vavrova P, Schuster B, Fuentes-Liso S, Potuckova L, Smrz D, Cernohouzova S, Draberova L, Bambouskova M, Draber P. Bugajev V, et al. J Lipid Res. 2021;62:100121. doi: 10.1016/j.jlr.2021.100121. Epub 2021 Sep 22. J Lipid Res. 2021. PMID: 34560079 Free PMC article.

9

ORMDL3 Functions as a Negative Regulator of Antigen-Mediated Mast Cell Activation via an ATF6-UPR-Autophagy-Dependent Pathway.

Li J, Ullah MA, Jin H, Liang Y, Lin L, Wang J, Peng X, Liao H, Li Y, Ge Y, Li L. Li J, et al. Front Immunol. 2021 Feb 19;12:604974. doi: 10.3389/fimmu.2021.604974. eCollection 2021. Front Immunol. 2021. PMID: 33679742 Free PMC article.

10

ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling.

Bugajev V, Halova I, Demkova L, Cernohouzova S, Vavrova P, Mrkacek M, Utekal P, Draberova L, Kuchar L, Schuster B, Draber P. Bugajev V, et al. Front Immunol. 2021 Feb 11;11:591975. doi: 10.3389/fimmu.2020.591975. eCollection 2020. Front Immunol. 2021. PMID: 33643282 Free PMC article.

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