PubMed (GeneRIF) for id: 22138

Year	Number of Results
2002	3
2003	2
2004	2
2005	1
2006	2
2007	3
2008	3
2009	4
2010	2
2011	7
2012	4
2013	5
2014	10
2015	5
2016	3
2017	3
2018	2
2019	8
2020	7
2021	4
2022	3
2023	2
2024	2

1

The TTN p. Tyr4418Ter mutation causes cardiomyopathy in human and mice.

Sun W, Liu X, Song L, Tao L, Lai K, Jiang H, Xiao H. Sun W, et al. PLoS One. 2024 Feb 21;19(2):e0296802. doi: 10.1371/journal.pone.0296802. eCollection 2024. PLoS One. 2024. PMID: 38381767 Free PMC article.

2

Titin takes centerstage among cytoskeletal contributions to myocardial passive stiffness.

Loescher CM, Linke WA. Loescher CM, et al. Cytoskeleton (Hoboken). 2024 Feb-Mar;81(2-3):184-187. doi: 10.1002/cm.21827. Epub 2023 Dec 29. Cytoskeleton (Hoboken). 2024. PMID: 38158587

3

Urine titin as a novel biomarker for Duchenne muscular dystrophy.

Ishii MN, Nakashima M, Kamiguchi H, Zach N, Kuboki R, Baba R, Hirakawa T, Suzuki K, Quinton M. Ishii MN, et al. Neuromuscul Disord. 2023 Apr;33(4):302-308. doi: 10.1016/j.nmd.2023.02.003. Epub 2023 Feb 13. Neuromuscul Disord. 2023. PMID: 36871413

4

Rbm20^ΔRRM Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness.

van den Berg M, Peters EL, van der Pijl RJ, Shen S, Heunks LMA, Granzier HL, Ottenheijm CAC. van den Berg M, et al. Int J Mol Sci. 2022 Dec 10;23(24):15689. doi: 10.3390/ijms232415689. Int J Mol Sci. 2022. PMID: 36555335 Free PMC article.

5

Titin force in muscle cells alters lattice order, thick and thin filament protein formation.

Hessel AL, Ma W, Mazara N, Rice PE, Nissen D, Gong H, Kuehn M, Irving T, Linke WA. Hessel AL, et al. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2209441119. doi: 10.1073/pnas.2209441119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409887 Free PMC article.

6

Active muscle stiffness is reduced during rapid unloading in muscles from TtnΔ112-158 mice with a large deletion to PEVK titin.

Hurley KL, Bassett JR, Monroy JA. Hurley KL, et al. J Exp Biol. 2022 Aug 15;225(16):jeb243584. doi: 10.1242/jeb.243584. Epub 2022 Aug 16. J Exp Biol. 2022. PMID: 35875854

7

Depletion of m⁶ A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin.

Gao S, Sun H, Chen K, Gu X, Chen H, Jiang L, Chen L, Zhang S, Liu Y, Shi D, Liang D, Xu L, Yang J, Ruan Y, Chen H, Shen B, Ma H, Chen YH. Gao S, et al. J Cell Mol Med. 2021 Dec;25(23):10879-10891. doi: 10.1111/jcmm.16955. Epub 2021 Oct 30. J Cell Mol Med. 2021. PMID: 34716659 Free PMC article.

8

Titin M-line insertion sequence 7 is required for proper cardiac function in mice.

Biquand A, Spinozzi S, Tonino P, Cosette J, Strom J, Elbeck Z, Knöll R, Granzier H, Lostal W, Richard I. Biquand A, et al. J Cell Sci. 2021 Sep 15;134(18):jcs258684. doi: 10.1242/jcs.258684. Epub 2021 Sep 17. J Cell Sci. 2021. PMID: 34401916 Free PMC article.

9

Solution NMR Structure of Titin N2A Region Ig Domain I83 and Its Interaction with Metal Ions.

Kelly C, Pace N, Gage M, Pfuhl M. Kelly C, et al. J Mol Biol. 2021 Jun 25;433(13):166977. doi: 10.1016/j.jmb.2021.166977. Epub 2021 Mar 31. J Mol Biol. 2021. PMID: 33811919 Free PMC article.

10

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant.

Jiang H, Hooper C, Kelly M, Steeples V, Simon JN, Beglov J, Azad AJ, Leinhos L, Bennett P, Ehler E, Kalisch-Smith JI, Sparrow DB, Fischer R, Heilig R, Isackson H, Ehsan M, Patone G, Huebner N, Davies B, Watkins H, Gehmlich K. Jiang H, et al. Basic Res Cardiol. 2021 Feb 26;116(1):14. doi: 10.1007/s00395-021-00853-z. Basic Res Cardiol. 2021. PMID: 33637999 Free PMC article.

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