PubMed (GeneRIF) for id: 21425

Year	Number of Results
2005	1
2006	1
2007	1
2009	1
2011	2
2012	1
2013	2
2014	3
2015	4
2016	10
2017	10
2018	12
2019	14
2020	18
2021	19
2022	11
2023	18
2024	5

1

Impaired TFEB-mediated autophagy-lysosome fusion promotes tubular cell cycle G2/M arrest and renal fibrosis by suppressing ATP6V0C expression and interacting with SNAREs.

Ren X, Wang J, Wei H, Li X, Tian Y, Wang Z, Yin Y, Guo Z, Qin Z, Wu M, Zeng X. Ren X, et al. Int J Biol Sci. 2024 Mar 3;20(5):1905-1926. doi: 10.7150/ijbs.91480. eCollection 2024. Int J Biol Sci. 2024. PMID: 38481802 Free PMC article.

2

TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.

Alesi N, Khabibullin D, Rosenthal DM, Akl EW, Cory PM, Alchoueiry M, Salem S, Daou M, Gibbons WF, Chen JA, Zhang L, Filippakis H, Graciotti L, Miceli C, Monfregola J, Vilardo C, Morroni M, Di Malta C, Napolitano G, Ballabio A, Henske EP. Alesi N, et al. Nat Commun. 2024 Jan 9;15(1):406. doi: 10.1038/s41467-023-44229-4. Nat Commun. 2024. PMID: 38195686 Free PMC article.

3

ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis.

Chen C, Zhang Z, Liu C, Sun P, Liu P, Li X. Chen C, et al. Cell Metab. 2024 Mar 5;36(3):498-510.e11. doi: 10.1016/j.cmet.2023.12.015. Epub 2024 Jan 4. Cell Metab. 2024. PMID: 38181789

4

Abnormal Cholesterol Metabolism and Lysosomal Dysfunction Induce Age-Related Hearing Loss by Inhibiting mTORC1-TFEB-Dependent Autophagy.

Lee YY, Ha J, Kim YS, Ramani S, Sung S, Gil ES, Choo OS, Jang JH, Choung YH. Lee YY, et al. Int J Mol Sci. 2023 Dec 15;24(24):17513. doi: 10.3390/ijms242417513. Int J Mol Sci. 2023. PMID: 38139347 Free PMC article.

5

Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries.

Fang Q, Jing G, Zhang Y, Wang H, Luo H, Xia Y, Jin Q, Liu Y, Zuo J, Yang C, Zhang X, Liu S, Wu X, Song X. Fang Q, et al. J Transl Med. 2023 Dec 17;21(1):916. doi: 10.1186/s12967-023-04796-y. J Transl Med. 2023. PMID: 38105228 Free PMC article.

6

Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.

Chen H, Yang X, Gao Y, Jiang H, Guo M, Zhou Y, Li C, Tan Y, Zhang Y, Xue W. Chen H, et al. Brain Res. 2024 Jan 15;1823:148683. doi: 10.1016/j.brainres.2023.148683. Epub 2023 Nov 20. Brain Res. 2024. PMID: 37992796 Free article.

7

TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy.

Wang B, Martini-Stoica H, Qi C, Lu TC, Wang S, Xiong W, Qi Y, Xu Y, Sardiello M, Li H, Zheng H. Wang B, et al. Nat Neurosci. 2024 Jan;27(1):48-62. doi: 10.1038/s41593-023-01494-2. Epub 2023 Nov 20. Nat Neurosci. 2024. PMID: 37985800

8

TFEB SUMOylation in macrophages accelerates atherosclerosis by promoting the formation of foam cells through inhibiting lysosomal activity.

Wang K, Zhou W, Hu G, Wang L, Cai R, Tian T. Wang K, et al. Cell Mol Life Sci. 2023 Nov 11;80(12):358. doi: 10.1007/s00018-023-04981-8. Cell Mol Life Sci. 2023. PMID: 37950772

9

Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease.

Wang X, Xie Y, Chen G, Lu Y, Wang D, Zhu L. Wang X, et al. J Neuroinflammation. 2023 Oct 20;20(1):240. doi: 10.1186/s12974-023-02931-6. J Neuroinflammation. 2023. PMID: 37864249 Free PMC article.

10

Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung.

Aufiero MA, Shlezinger N, Gjonbalaj M, Mills KAM, Ballabio A, Hohl TM. Aufiero MA, et al. Infect Immun. 2023 Nov 16;91(11):e0021723. doi: 10.1128/iai.00217-23. Epub 2023 Oct 20. Infect Immun. 2023. PMID: 37861312 Free PMC article.

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