PubMed (GeneRIF) for id: 14042

Year	Number of Results
2003	1
2004	2
2005	1
2008	1
2009	3
2010	6
2011	2
2012	2
2013	2
2014	1
2015	2
2017	1
2019	1
2020	1
2021	1
2022	2
2024	0

1

Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.

Mundy C, Chung J, Koyama E, Bunting S, Mahimkar R, Pacifici M. Mundy C, et al. J Orthop Res. 2022 Oct;40(10):2391-2401. doi: 10.1002/jor.25260. Epub 2022 Jan 22. J Orthop Res. 2022. PMID: 34996123 Free PMC article.

2

Obesity induced Ext1 reduction mediates the occurrence of NAFLD.

Wang M, Li B, Qin F, Ye J, Jin L. Wang M, et al. Biochem Biophys Res Commun. 2022 Jan 22;589:123-130. doi: 10.1016/j.bbrc.2021.12.017. Epub 2021 Dec 7. Biochem Biophys Res Commun. 2022. PMID: 34906902

3

Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.

Bachvarova V, Dierker T, Esko J, Hoffmann D, Kjellen L, Vortkamp A. Bachvarova V, et al. Matrix Biol. 2020 Nov;93:43-59. doi: 10.1016/j.matbio.2020.03.006. Epub 2020 Mar 20. Matrix Biol. 2020. PMID: 32201365 Free article.

4

Loss of the Heparan Sulfate Proteoglycan Glypican5 Facilitates Long-Range Sonic Hedgehog Signaling.

Guo W, Roelink H. Guo W, et al. Stem Cells. 2019 Jul;37(7):899-909. doi: 10.1002/stem.3018. Epub 2019 May 13. Stem Cells. 2019. PMID: 30977233 Free PMC article.

5

Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development.

He H, Huang M, Sun S, Wu Y, Lin X. He H, et al. PLoS Genet. 2017 Aug 31;13(8):e1006992. doi: 10.1371/journal.pgen.1006992. eCollection 2017 Aug. PLoS Genet. 2017. PMID: 28859094 Free PMC article.

6

Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling.

Zhang R, Cao P, Yang Z, Wang Z, Wu JL, Chen Y, Pan Y. Zhang R, et al. PLoS One. 2015 Aug 21;10(8):e0136518. doi: 10.1371/journal.pone.0136518. eCollection 2015. PLoS One. 2015. PMID: 26295701 Free PMC article.

7

Effect of systemic heparan sulfate haploinsufficiency on steady state hematopoiesis and engraftment of hematopoietic stem cells.

Shekels LL, Buelt-Gebhardt M, Gupta P. Shekels LL, et al. Blood Cells Mol Dis. 2015 Jun;55(1):3-9. doi: 10.1016/j.bcmd.2015.03.001. Epub 2015 Mar 25. Blood Cells Mol Dis. 2015. PMID: 25976459

8

Loss of function in heparan sulfate elongation genes EXT1 and EXT 2 results in improved nitric oxide bioavailability and endothelial function.

Mooij HL, Cabrales P, Bernelot Moens SJ, Xu D, Udayappan SD, Tsai AG, van der Sande MA, de Groot E, Intaglietta M, Kastelein JJ, Dallinga-Thie GM, Esko JD, Stroes ES, Nieuwdorp M. Mooij HL, et al. J Am Heart Assoc. 2014 Dec 2;3(6):e001274. doi: 10.1161/JAHA.114.001274. J Am Heart Assoc. 2014. PMID: 25468659 Free PMC article.

9

Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.

Huegel J, Mundy C, Sgariglia F, Nygren P, Billings PC, Yamaguchi Y, Koyama E, Pacifici M. Huegel J, et al. Dev Biol. 2013 May 1;377(1):100-12. doi: 10.1016/j.ydbio.2013.02.008. Epub 2013 Mar 1. Dev Biol. 2013. PMID: 23458899 Free PMC article.

10

Involvement of Ext1 and heparanase in migration of mouse FBJ osteosarcoma cells.

Wang Y, Yang X, Yamagata S, Yamagata T, Sato T. Wang Y, et al. Mol Cell Biochem. 2013 Jan;373(1-2):63-72. doi: 10.1007/s11010-012-1475-8. Epub 2012 Oct 10. Mol Cell Biochem. 2013. PMID: 23054193

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