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PubMed (GeneRIF) for id: 13560

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The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Lacroix M, Linares LK, Rueda-Rincon N, Bloch K, Di Michele M, De Blasio C, Fau C, Gayte L, Blanchet E, Mairal A, Derua R, Cardona F, Beuzelin D, Annicotte JS, Pirot N, Torro A, Tinahones FJ, Bernex F, Bertrand-Michel J, Langin D, Fajas L, Swinnen JV, Le Cam L. Lacroix M, et al. Nat Commun. 2021 Dec 2;12(1):7037. doi: 10.1038/s41467-021-27307-3. Nat Commun. 2021. PMID: 34857760 Free PMC article.
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity.
Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, Gayte L, Casas F, Pessemesse L, Heuillet M, Bellvert F, Portais JC, Berthet C, Bernex F, Brivet M, Boutron A, Le Cam L, Sardet C. Lacroix M, et al. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10998-1003. doi: 10.1073/pnas.1602754113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621446 Free PMC article.
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.
Goguet-Rubio P, Seyran B, Gayte L, Bernex F, Sutter A, Delpech H, Linares LK, Riscal R, Repond C, Rodier G, Kirsh O, Touhami J, Noel J, Vincent C, Pirot N, Pavlovic G, Herault Y, Sitbon M, Pellerin L, Sardet C, Lacroix M, Le Cam L. Goguet-Rubio P, et al. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):11004-9. doi: 10.1073/pnas.1602751113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621431 Free PMC article.
E4F1 is a master regulator of CHK1-mediated functions.
Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. Grote D, et al. Cell Rep. 2015 Apr 14;11(2):210-9. doi: 10.1016/j.celrep.2015.03.019. Epub 2015 Apr 2. Cell Rep. 2015. PMID: 25843717 Free article.
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.
Hatchi E, Rodier G, Lacroix M, Caramel J, Kirsh O, Jacquet C, Schrepfer E, Lagarrigue S, Linares LK, Lledo G, Tondeur S, Dubus P, Sardet C, Le Cam L. Hatchi E, et al. J Exp Med. 2011 Jul 4;208(7):1403-17. doi: 10.1084/jem.20101995. Epub 2011 Jun 27. J Exp Med. 2011. PMID: 21708927 Free PMC article.
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.
Lacroix M, Caramel J, Goguet-Rubio P, Linares LK, Estrach S, Hatchi E, Rodier G, Lledo G, de Bettignies C, Thépot A, Deraison C, Chébli K, Hovnanian A, Hainaut P, Dubus P, Sardet C, Le Cam L. Lacroix M, et al. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21076-81. doi: 10.1073/pnas.1010167107. Epub 2010 Nov 18. Proc Natl Acad Sci U S A. 2010. PMID: 21088222 Free PMC article.