PubMed (GeneRIF) for id: 104158

Year	Number of Results
2004	1
2005	1
2010	2
2012	1
2015	1
2019	1
2021	1
2022	1
2023	1
2024	0

1

Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development.

Gan C, Wang J, Wang Y, Martínez-Chávez A, Hillebrand M, de Vries N, Beukers J, Lebre MC, Wagenaar E, Rosing H, Klarenbeek S, Bleijerveld OB, Song JY, Altelaar M, Beijnen JH, Schinkel AH. Gan C, et al. Biomed Pharmacother. 2023 Aug;164:114956. doi: 10.1016/j.biopha.2023.114956. Epub 2023 May 31. Biomed Pharmacother. 2023. PMID: 37267638 Free article.

2

Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice.

Li G, Li X, Yang L, Wang S, Dai Y, Fekry B, Veillon L, Tan L, Berdeaux R, Eckel-Mahan K, Lorenzi PL, Zhao Z, Lehner R, Sun K. Li G, et al. Life Sci Alliance. 2022 Apr 22;5(8):e202101209. doi: 10.26508/lsa.202101209. Print 2022 Aug. Life Sci Alliance. 2022. PMID: 35459739 Free PMC article.

3

Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver.

Lian J, van der Veen JN, Watts R, Jacobs RL, Lehner R. Lian J, et al. J Lipid Res. 2021;62:100093. doi: 10.1016/j.jlr.2021.100093. Epub 2021 Jun 18. J Lipid Res. 2021. PMID: 34153284 Free PMC article.

4

Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation.

Lian J, Watts R, Quiroga AD, Beggs MR, Alexander RT, Lehner R. Lian J, et al. J Lipid Res. 2019 Apr;60(4):880-891. doi: 10.1194/jlr.M092544. Epub 2019 Feb 8. J Lipid Res. 2019. PMID: 30737251 Free PMC article.

5

Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway.

Chen R, Wang Y, Ning R, Hu J, Liu W, Xiong J, Wu L, Liu J, Hu G, Yang J. Chen R, et al. Xenobiotica. 2015;45(9):782-93. doi: 10.3109/00498254.2015.1020353. Epub 2015 Jul 27. Xenobiotica. 2015. PMID: 25801056

6

Ces3/TGH deficiency improves dyslipidemia and reduces atherosclerosis in Ldlr(-/-) mice.

Lian J, Quiroga AD, Li L, Lehner R. Lian J, et al. Circ Res. 2012 Sep 28;111(8):982-90. doi: 10.1161/CIRCRESAHA.112.267468. Epub 2012 Aug 7. Circ Res. 2012. PMID: 22872154

7

Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression.

Wang H, Wei E, Quiroga AD, Sun X, Touret N, Lehner R. Wang H, et al. Mol Biol Cell. 2010 Jun 15;21(12):1991-2000. doi: 10.1091/mbc.e09-05-0364. Epub 2010 Apr 21. Mol Biol Cell. 2010. PMID: 20410140 Free PMC article.

8

Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure.

Wei E, Ben Ali Y, Lyon J, Wang H, Nelson R, Dolinsky VW, Dyck JR, Mitchell G, Korbutt GS, Lehner R. Wei E, et al. Cell Metab. 2010 Mar 3;11(3):183-93. doi: 10.1016/j.cmet.2010.02.005. Cell Metab. 2010. PMID: 20197051 Free article.

9

C/EBPalpha activates the transcription of triacylglycerol hydrolase in 3T3-L1 adipocytes.

Wei E, Lehner R, Vance DE. Wei E, et al. Biochem J. 2005 Jun 15;388(Pt 3):959-66. doi: 10.1042/BJ20041442. Biochem J. 2005. PMID: 15752068 Free PMC article.

10

Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase.

Soni KG, Lehner R, Metalnikov P, O'Donnell P, Semache M, Gao W, Ashman K, Pshezhetsky AV, Mitchell GA. Soni KG, et al. J Biol Chem. 2004 Sep 24;279(39):40683-9. doi: 10.1074/jbc.M400541200. Epub 2004 Jun 25. J Biol Chem. 2004. PMID: 15220344 Free article.

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