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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
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1998 2
2001 1
2002 1
2003 1
2004 1
2005 1
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2007 1
2008 2
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2016 1
2024 0

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PubMed (OMIM) for id: 5170

18 results

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Page 1
Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors.
Cordón-Barris L, Pascual-Guiral S, Yang S, Giménez-Llort L, Lope-Piedrafita S, Niemeyer C, Claro E, Lizcano JM, Bayascas JR. Cordón-Barris L, et al. Mol Cell Biol. 2016 Nov 14;36(23):2967-2982. doi: 10.1128/MCB.00230-16. Print 2016 Dec 1. Mol Cell Biol. 2016. PMID: 27644329 Free PMC article.
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Bayascas JR, et al. Mol Cell Biol. 2008 May;28(10):3258-72. doi: 10.1128/MCB.02032-07. Epub 2008 Mar 17. Mol Cell Biol. 2008. PMID: 18347057 Free PMC article.
Essential role of PDK1 in regulating endothelial cell migration.
Primo L, di Blasio L, Roca C, Droetto S, Piva R, Schaffhausen B, Bussolino F. Primo L, et al. J Cell Biol. 2007 Mar 26;176(7):1035-47. doi: 10.1083/jcb.200607053. Epub 2007 Mar 19. J Cell Biol. 2007. PMID: 17371830 Free PMC article.
18 results