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33707553,31316132,29575431,26645482,26079855,25659534,25031732,23826330,23771793,23420874,23159538,23131845,22001015,21195589,21185312,20596655,19716163,17466257,15368963,11878897,10395476,10090780,10051406,9642078,8794768,8670205,8663276,8585965,8386805,8178156,7881903,7716522,7486658,917890,38182563,37661474,37626338,35970002,34232285,33795832,33323827,33171874,32752665,31882608,31844042,31634528,31164678,30651372,30474799,30282717,30069987,29730656,28360125,28166272,27449805,27264952,26188370,26103942,25688510,25413232,24882360,24697349,24391994,24259669,24100123,23922722,22882974,22553920,22360309,21072043,20850195,20124721,19668218,19337752,19323566,18778683,18425376,17991782,17849173,17616655,17276458,16760435,16407827,16382132,15879090,15812354,15782189,15326489,15182856,15122321,12839496,12748278,12531430,12388170,12345679,12213123,12162872,12007418,12006650,12005431,11997181,11827484,11733534,11707405,11527382,11406576,11384839,11352655,11278754,11278583,11063574,10970810,10940627,10903901,10887132,10521482,10490839,10359574,10356320,10354709,10318918,9922133,9891051,9830057,9668219,9299436,9281317,9254595,9175774,9171350,9038219,9016807,8994038,8986819,8824292,8702859,8700507,8672490,8670803,8663178,8662889,8649804,8630373,8585605,8547634,8253073,8119878,7935391,7809090,7773779,7759531,7744881,7737969,7559579,7527391,7527043,7524086,7511210,7500025,7488107,7488076,1384039,35747966,34697226,34162761,32692718,32160453,31320611,30054970,28978467,28087344,27059931,26885689,26511382,25041730,24939894,24902122,24708867,24440983,24399467,23946459,23916875,23700486,23334917,23154388,22726438,22536782,22396725,22094095,22057045,22027826,21508312,21222362,21189249,20554525,20005866,19924227,19879355,19254954,18789888,18307981,18192688,17971399,17904548,17689925,17409413,16912232,15735675,15635092,15536091,15210722,12852788,12522133,12485888,12400011,12399475,12242309,12242006,12173038,12171928,12091307,11897833,11882361,11684012,11546790,11505033,11449366,11399323,11394904,11371563,11314042,11302736,11263968,11006130,10906142,10900203,10820378,10781592,10716926,10377264,10224664,10212213,10087612,10049786,9927207,9742218,9733714,9722576,9710588,9705962,9694876,9685397,9590294,9553137,9516488,9480847,9478994,9447984,9393871,9388224,9380408,9178913,9135065,9019171,8955163,8943348,8939605,8816480,8810340,8780727,8695851,8662748,8657152,8649391,8626404,8576157,8479541,8294403,8195176,8195171,8188688,8084588,8083187,8063801,8041791,7982917,7970715,7929073,7862111,7806213,7798267,7791764,7744812,7737275,7675449,7665556,7664271,7629138,7629070,7592693,7537740,7534299,7523859,7522233,7518560,7512734,7506413,1322798,38459011,37798786,36948698,34032851,32364763,31235500,30544639,28912526,28046066,27927989,27802291,26551075,25140053,25092874,24475931,24407288,23267066,23178716,22505611,22327338,21725282,20700730,20618341,20067773,19682241,19273609,18003605,17452978,17242169,17094785,16582911,16520382,16103119,16038803,15151996,14725908,12898421,12810066,12730204,12441060,11792427,11746524,11729184,11606575,11551227,11533253,11439336,11433379,11370743,10980613,10940929,10822386,10748052,10595738,10570290,10559276,10488157,10386953,10329689,10229072,10080542,9852124,9824671,9670936,9660480,9541596,9488479,9484780,9434624,9416834,9407116,9374537,9361008,9295052,9254654,9242692,9126968,9083103,9079622,9050991,9047383,9032244,9020117,9013873,8995399,8995358,8985255,8955135,8900205,8649368,8647288,8626525,8596638,8536716,8491186,8388384,8194526,8022809,7650032,7642542,7559490,7556090,7529874,7516467,7514169,7510700,7504175,7478529,29656494,26212011,25872741,25819436,24430869,22344067,20124286,19836242,19735729,19433454,19109251,17235283,16955467,16339550,16253990,15929943,15888547,15782196,15558030,15556869,15143164,14560030,13129930,12941616,12402043,12220636,12186904,12149229,12023017,11997436,11726515,11606067,11466354,11432792,10942756,10921882,10891441,10811803,10806474,10747947,10706702,10636929,10542228,10330178,10319320,10224278,10207103,10204582,10022120,9891069,9890893,9886492,9851874,9819383,9804835,9788432,9736607,9614102,9544989,9428629,9368064,9356464,9307968,9259313,9020193,9019162,9009162,8995445,8723348,8695800,8662907,8662733,8647802,8647120,8633037,8621459,8262059,8235613,8183561,8112292,7926767,7675451,7642581,7629168,7597091,7544353,7515480,33627783,31651330,28690151,25535246,24003223,23532252,23460737,21745501,21725358,21278786,21179510,19509291,18231572,17875712,16906159,16219545,15677445,15187135,14722116,14506255,12624098,12529371,12486104,11923305,11782427,11551923,11509578,11418612,11408594,11278465,11157975,10973965,10913131,10781580,10734310,10648629,10477741,10206341,10202139,10086340,10085134,10068651,10025673,9797459,9716598,9632781,9632734,9569023,9565634,9461587,9362449,9234717,9148935,8950973,8816475,8665853,8647858,8570203,7739560,7706237,7523381,30610177,28213521,23799367,21278788,20933011,20159979,18647389,16938345,16899217,16818765,16137687,15784897,15173068,14557262,12615911,12558988,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Results by year

Year	Number of Results
1977	1
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926 results

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A new bioinformatics approach identifies overexpression of GRB2 as a poor prognostic biomarker for prostate cancer.

Iwata T, Sedukhina AS, Kubota M, Oonuma S, Maeda I, Yoshiike M, Usuba W, Minagawa K, Hames E, Meguro R, Cho S, Chien SHH, Urabe S, Pae S, Palanisamy K, Kumai T, Yudo K, Kikuchi E, Sato K. Iwata T, et al. Sci Rep. 2021 Mar 11;11(1):5696. doi: 10.1038/s41598-021-85086-9. Sci Rep. 2021. PMID: 33707553 Free PMC article.

Evaluation of genetic susceptibility between systemic lupus erythematosus and GRB2 gene.

Xu M, Liu Y, Li X, Cheng C, Liu Y, Dong W, Du S, Xiao S. Xu M, et al. Sci Rep. 2019 Jul 17;9(1):10335. doi: 10.1038/s41598-019-46827-z. Sci Rep. 2019. PMID: 31316132 Free PMC article.

Integrated transcriptomic and proteomic analyses reveal ɑ-lipoic acid-regulated cell proliferation via Grb2-mediated signalling in hepatic cancer cells.

Yang L, Wang X, Xu J, Wen Y, Zhang M, Lu J, Wang R, Sun X. Yang L, et al. J Cell Mol Med. 2018 Jun;22(6):2981-2992. doi: 10.1111/jcmm.13447. Epub 2018 Mar 25. J Cell Mol Med. 2018. PMID: 29575431 Free PMC article.

Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.

Papaioannou D, Geibel S, Kunze MB, Kay CW, Waksman G. Papaioannou D, et al. Protein Sci. 2016 Mar;25(3):627-37. doi: 10.1002/pro.2856. Epub 2015 Dec 29. Protein Sci. 2016. PMID: 26645482 Free PMC article.

Regions outside of conserved PxxPxR motifs drive the high affinity interaction of GRB2 with SH3 domain ligands.

Bartelt RR, Light J, Vacaflores A, Butcher A, Pandian M, Nash P, Houtman JC. Bartelt RR, et al. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2560-9. doi: 10.1016/j.bbamcr.2015.06.002. Epub 2015 Jun 12. Biochim Biophys Acta. 2015. PMID: 26079855 Free PMC article.

Quantitative proteomics reveals the downregulation of GRB2 as a prominent node of F806-targeted cell proliferation network.

Li LY, Zhang K, Jiang H, Xie YM, Liao LD, Chen B, Du ZP, Zhang PX, Chen H, Huang W, Jia W, Cao HH, Zheng W, Li EM, Xu LY. Li LY, et al. J Proteomics. 2015 Mar 18;117:145-55. doi: 10.1016/j.jprot.2015.01.016. Epub 2015 Feb 7. J Proteomics. 2015. PMID: 25659534

Overexpression of GRB2 is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma.

Li LY, Li EM, Wu ZY, Cao HH, Shen JH, Xu XE, Chen B, Wu JY, Xu LY. Li LY, et al. Int J Clin Exp Pathol. 2014 May 15;7(6):3132-40. eCollection 2014. Int J Clin Exp Pathol. 2014. PMID: 25031732 Free PMC article.

A Novel Phosphopeptide Microarray Based Interactome Map in Breast Cancer Cells Reveals Phosphoprotein-GRB2 Cell Signaling Networks.

Krishnamoorthy S, Liu Z, Hong A, Zhu R, Chen H, Li T, Zhou X, Gao X. Krishnamoorthy S, et al. PLoS One. 2013 Jun 27;8(6):e67634. doi: 10.1371/journal.pone.0067634. Print 2013. PLoS One. 2013. PMID: 23826330 Free PMC article.

Suppression of Grb2 expression improved hepatic steatosis, oxidative stress, and apoptosis induced by palmitic acid in vitro partly through insulin signaling alteration.

Shan X, Miao Y, Fan R, Song C, Wu G, Wan Z, Zhu J, Sun G, Zha W, Mu X, Zhou G, Chen Y. Shan X, et al. In Vitro Cell Dev Biol Anim. 2013 Sep;49(8):576-82. doi: 10.1007/s11626-013-9646-9. Epub 2013 Jun 15. In Vitro Cell Dev Biol Anim. 2013. PMID: 23771793

Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.

Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE. Ahmed Z, et al. J Cell Biol. 2013 Feb 18;200(4):493-504. doi: 10.1083/jcb.201204106. J Cell Biol. 2013. PMID: 23420874 Free PMC article.

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926 results

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