PubMed for id: 21936

Year	Number of Results
1997	1
1999	1
2000	4
2001	3
2002	4
2003	4
2004	9
2005	11
2006	8
2007	5
2008	10
2009	8
2010	10
2011	11
2012	8
2013	6
2014	5
2015	7
2016	6
2017	5
2018	2
2019	4
2020	8
2021	4
2022	1
2024	1

1

GITR agonistic stimulation enhances the anti-tumor immune response in a mouse model of ESCC.

Wiles KN, Tsikretsis LE, Alioto CM, Hermida de Viveiros PA, Villaflor VM, Tétreault MP. Wiles KN, et al. Carcinogenesis. 2022 Oct 22;43(9):908-918. doi: 10.1093/carcin/bgac064. Carcinogenesis. 2022. PMID: 35880612 Free PMC article.

2

Effects of protein-protein interface disruptors at the ligand of the glucocorticoid-induced tumor necrosis factor receptor-related gene (GITR).

Platania CBM, Ronchetti S, Riccardi C, Migliorati G, Marchetti MC, Di Paola L, Lazzara F, Drago F, Salomone S, Bucolo C. Platania CBM, et al. Biochem Pharmacol. 2020 Aug;178:114110. doi: 10.1016/j.bcp.2020.114110. Epub 2020 Jun 20. Biochem Pharmacol. 2020. PMID: 32569630

3

Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types.

Zhu MMT, Burugu S, Gao D, Yu J, Kos Z, Leung S, Horst BA, Nielsen TO. Zhu MMT, et al. Mod Pathol. 2020 Sep;33(9):1753-1763. doi: 10.1038/s41379-020-0550-z. Epub 2020 Apr 29. Mod Pathol. 2020. PMID: 32350416 Free article.

4

GITR differentially affects lung effector T cell subpopulations during influenza virus infection.

Chu KL, Batista NV, Girard M, Law JC, Watts TH. Chu KL, et al. J Leukoc Biol. 2020 Jun;107(6):953-970. doi: 10.1002/JLB.4AB1219-254R. Epub 2020 Mar 3. J Leukoc Biol. 2020. PMID: 32125017

5

Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.

Vashist N, Trittel S, Ebensen T, Chambers BJ, Guzmán CA, Riese P. Vashist N, et al. Front Immunol. 2018 Mar 22;9:505. doi: 10.3389/fimmu.2018.00505. eCollection 2018. Front Immunol. 2018. PMID: 29623077 Free PMC article.

6

GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory.

Durham NM, Holoweckyj N, MacGill RS, McGlinchey K, Leow CC, Robbins SH. Durham NM, et al. J Immunother Cancer. 2017 Jun 20;5:47. doi: 10.1186/s40425-017-0247-0. eCollection 2017. J Immunother Cancer. 2017. PMID: 28649380 Free PMC article.

7

Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells.

Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, Sriram V, Bailey WJ, Herzyk D, McClanahan TK, Willingham A, Beebe AM, Sadekova S. Sukumar S, et al. Cancer Res. 2017 Aug 15;77(16):4378-4388. doi: 10.1158/0008-5472.CAN-16-1439. Epub 2017 Jun 13. Cancer Res. 2017. PMID: 28611044

8

A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist.

Leyland R, Watkins A, Mulgrew KA, Holoweckyj N, Bamber L, Tigue NJ, Offer E, Andrews J, Yan L, Mullins S, Oberst MD, Coates Ulrichsen J, Leinster DA, McGlinchey K, Young L, Morrow M, Hammond SA, Mallinder P, Herath A, Leow CC, Wilkinson RW, Stewart R. Leyland R, et al. Clin Cancer Res. 2017 Jul 1;23(13):3416-3427. doi: 10.1158/1078-0432.CCR-16-2000. Epub 2017 Jan 9. Clin Cancer Res. 2017. PMID: 28069723

9

Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4+ T-Cell Responses-Brief Report.

Meiler S, Smeets E, Winkels H, Shami A, Pascutti MF, Nolte MA, Beckers L, Weber C, Gerdes N, Lutgens E. Meiler S, et al. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1748-52. doi: 10.1161/ATVBAHA.116.307354. Epub 2016 Jul 21. Arterioscler Thromb Vasc Biol. 2016. PMID: 27444204

10

Blockade of Glucocorticoid-Induced Tumor Necrosis Factor-Receptor-Related Protein Signaling Ameliorates Murine Collagen-Induced Arthritis by Modulating Follicular Helper T Cells.

Ma J, Feng D, Wei Y, Tian J, Tang X, Rui K, Lu L, Xu H, Wang S. Ma J, et al. Am J Pathol. 2016 Jun;186(6):1559-67. doi: 10.1016/j.ajpath.2016.02.010. Epub 2016 Apr 20. Am J Pathol. 2016. PMID: 27106763 Free article.

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