PubMed for id: 19247

Year	Number of Results
1993	4
1994	4
1995	1
1996	7
1997	7
1998	4
1999	8
2000	9
2001	5
2002	12
2003	23
2004	14
2005	24
2006	20
2007	17
2008	16
2009	26
2010	20
2011	23
2012	23
2013	27
2014	34
2015	18
2016	17
2017	30
2018	27
2019	19
2020	16
2021	12
2022	14
2023	17
2024	5

1

Allosteric inhibitor of SHP2 enhances macrophage endocytosis and bacteria elimination by increasing caveolae activation and protects against bacterial sepsis.

Li T, Xu B, Li W, Cheng X, Tantai W, Zheng H, Zhao L, Li N, Han C. Li T, et al. Pharmacol Res. 2024 Mar;201:107096. doi: 10.1016/j.phrs.2024.107096. Epub 2024 Feb 4. Pharmacol Res. 2024. PMID: 38320736 Free article.

2

Hepatic protein tyrosine phosphatase Shp2 disruption mitigates the adverse effects of ethanol in the liver by modulating oxidative stress and ERK signaling.

Hsu MF, LeBleu G, Flores L, Parkhurst A, Nagy LE, Haj FG. Hsu MF, et al. Life Sci. 2024 Mar 1;340:122451. doi: 10.1016/j.lfs.2024.122451. Epub 2024 Jan 20. Life Sci. 2024. PMID: 38253311

3

Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution.

Liu M, Ji M, Cheng J, Li Y, Tian Y, Zhao H, Wang Y, Zhu S, Zhang L, Xu X, Feng GS, Liang X, Bao H, Tang Y, Kong S, Lu J, Wang H, Lu Z, Deng W. Liu M, et al. Nat Commun. 2023 Nov 14;14(1):7356. doi: 10.1038/s41467-023-43102-8. Nat Commun. 2023. PMID: 37963860 Free PMC article.

4

Protein Tyrosine Phosphatase SHP2 in Macrophages Acts as an Antiatherosclerotic Regulator in Mice.

Wu C, Zheng P, Ma L, Xu C, Hu L, Yang Z, Fei F, Shen Z, Zhang X, Wu Z, Cheng H, Mao W, Ke Y. Wu C, et al. Arterioscler Thromb Vasc Biol. 2024 Jan;44(1):202-217. doi: 10.1161/ATVBAHA.123.319663. Epub 2023 Nov 9. Arterioscler Thromb Vasc Biol. 2024. PMID: 37942607

5

An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression.

Luo Q, Liu Y, Shi K, Shen X, Yang Y, Liang X, Lu L, Qiao W, Chen A, Hong D, Sun Y, Xu Q. Luo Q, et al. Immunity. 2023 Sep 12;56(9):2006-2020.e6. doi: 10.1016/j.immuni.2023.06.012. Epub 2023 Jul 19. Immunity. 2023. PMID: 37473759

6

Macrophage-derived SHP-2 inhibits the metastasis of colorectal cancer via Tie2-PI3K signals.

Wu X, Guan S, Lu Y, Xue J, Yu X, Zhang QI, Wang X, Li T. Wu X, et al. Oncol Res. 2023 Apr 10;31(2):125-139. doi: 10.32604/or.2023.028657. eCollection 2023. Oncol Res. 2023. PMID: 37304233 Free PMC article.

7

SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor.

Chen L, Zhao W, Li M, Yang Y, Tian C, Zhang D, Chang Z, Zhang Y, Zhao ZJ, Chen Y, Ma L. Chen L, et al. Reproduction. 2023 Jun 9;166(1):37-53. doi: 10.1530/REP-22-0367. Print 2023 Jul 1. Reproduction. 2023. PMID: 37184079 Free PMC article.

8

The Cell-Specific Role of SHP2 in Regulating Bone Homeostasis and Regeneration Niches.

Zhang J, Ye C, Zhu Y, Wang J, Liu J. Zhang J, et al. Int J Mol Sci. 2023 Jan 22;24(3):2202. doi: 10.3390/ijms24032202. Int J Mol Sci. 2023. PMID: 36768520 Free PMC article. Review.

9

Deficiency of the Src homology phosphatase 2 in podocytes is associated with renoprotective effects in mice under hyperglycemia.

Hsu MF, Ito Y, Afkarian M, Haj FG. Hsu MF, et al. Cell Mol Life Sci. 2022 Sep 14;79(10):516. doi: 10.1007/s00018-022-04517-6. Cell Mol Life Sci. 2022. PMID: 36102977 Free PMC article.

10

Tyrosine phosphatase SHP2 in ovarian granulosa cells balances follicular development by inhibiting PI3K/AKT signaling.

Wei X, Zheng L, Tian Y, Wang H, Su Y, Feng G, Wang C, Lu Z. Wei X, et al. J Mol Cell Biol. 2022 Sep 27;14(7):mjac048. doi: 10.1093/jmcb/mjac048. J Mol Cell Biol. 2022. PMID: 36002018 Free PMC article.

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